Mark Landreneau
Clinician

About Me

In Man’s Search for Meaning, Holocaust survivor and neuropsychiatrist Victor Frankl

offered a thought experiment: live your life as though it were the second time around.

Imagine on your death bed the universe offered you a do over, and you start over today.

Now you are free. You already suffered and made your mistakes. Live in the present

and make choices with your authentic self. Imagine becoming the best version of you.

What might be possible?

I work to provide my patients the safety, skills, and care to live the second time around.

Psychedelic medications like ketamine can serve as a tool to access and heal core

wounds, a form of reparenting oneself. Within this relational and developmental

framework, my practice focuses on mood disorders such as depression, anxiety, and

trauma.

What is an unusual historical artifact is that the nervous system is the only organ system

claimed by two specialties—neurology and psychiatry. I trained as a general neurologist

and neurocritical care physician at Yale, learning to care for some of the sickest patients

in the hospital. As I grew deeper into my work and witnessed the emotional toll of

“neurological” disease, I became more and more interested in problems and solutions at

the frontier of neuropsychiatry. I started working at the collaborative, community based

psychiatry clinic here at Centered. I work with my patients in a holistic, humanistic

way—life stories and lived experiences over labels. My general approach is to use the

fewest, lowest dose medications as necessary and pair them with therapeutic, growth-

oriented work.

In addition to neuroscience, I lean on wisdom and techniques from a variety of schools

of therapy including but not limited to Acceptance and Commitment Therapy, Internal

Family Systems, Emotion Focused Therapy, and Trauma Incident Reduction. I also

value a variety of traditional and non-traditional wisdom traditions. I want to empower

my patients in their own healing journeys. I have particular interests in mood disorders,

traumatic brain injury, the autistic spectrum, attention problems, grief, identity issues,

end of life, and neuropsychiatric problems amenable to psychedelic approaches. I also

emphasize general health and wellness along with motivation, goal setting, and life

restructuring.

In my spare time, I enjoy adventures in nature with my wife and kids, playing pickup

soccer with the local crowd, reading and writing non-fiction and fiction, exploring the

arts, cooking for others, and pondering the night sky.

Education, Training, and Certification

  • BA, Philosophy, University of Dallas, 2007

  • MD, Columbia University Vagelos College of Physicians and Surgeons, 2012

  • Neurology Residency, Yale-New Haven Hospital, 2016

  • Neurocritical Care and Emergency Neurology, Yale New-Haven Hospital, 2018

  • American Board of Psychiatry and Neurology, Neurology Certification, 2016

  • Brain Stimulation Intensive Training, TMS Track, Medical University of South Carolina,

  • 2023

  • Ketamine Training Center, Fundamentals of Ketamine Assisted Psychotherapy, 2024

  • Colorado Clinical Facilitator of Natural Medicine, InnerTrek Training Program, 2026